崔宗强

研究方向

1.单病毒示踪

2.病毒-宿主相互作用机制

3.新型纳米疫苗教育及工作经历

教育及工作经历

2011.12-至今，中国科学院武汉病毒研究所，研究员，博导

2008.12-2011.12，中国科学院武汉病毒研究所，副研，硕导

2005.07-2008.12，中国科学院武汉病毒研究所，助研

2002.09-2005.07，中国科学院武汉病毒研究所，博士

1999.09-2002.07，华中农业大学，硕士

1995.09-1999.07，华中农业大学，学士近五年承担项目

近五年承担项目

1.国家自然科学基金杰出青年基金项目

2.中国科学院战略性先导科技专项B课题

3.国家自然科学基金重大研究计划培育项目

4.中国科学院前沿科学重点研究项目“青年拔尖科学家”项目

近五年代表性论文

1. Ji Liu; Zhengyuan Guo; Wei Li; Xiaowei Zhang; Cuiqin Liang; Zongqiang Cui*; Packaging Quantum Dots in Viral Particles via a Strep-tag II/Streptavidin System for Single-Virus Tracking, Nano Letters, 2024, 24(9)：2821-2830. 

2. Xuefan Wu; Wei Li; Heng Rong; Jingdi Pan; Xiaowei Zhang; Qinxue Hu; Zheng-Li Shi; Xian-En Zhang; Zongqiang Cui; A Nanoparticle Vaccine Displaying Conserved Epitopes of the Preexisting Neutralizing Antibody Confers Broad Protection against SARS-CoV-2 Variants, ACS Nano, 2024, 18(27)：17749-17763. 

3. Siying Li, Hui Yang, Falin Tian, Wei Li, Hongda Wang, Xinghua Shi*, Zongqiang Cui*, Yuping Shan*. Unveiling the Dynamic Mechanism of SARS-CoV-2 Entry Host Cells at the Single-Particle Level. ACS Nano, 2024 Oct 15;18(41):27891-27904.

4. Xianxun Sun; Tao Tian; Yindong Lian; Zongqiang Cui; Current Advances in Viral Nanoparticles for Biomedicine, ACS Nano, 2024, 18(50)：33827-33863.

5. Jingdi Pan, Qihui Wang, Mi Qi, Jianjun Chen, Xuefan Wu, Xiaowei Zhang, Wei Li, Xian-En Zhang, Zongqiang Cui*. An Intranasal Multivalent Epitope-Based Nanoparticle Vaccine Confers Broad Protection against Divergent Influenza Viruses. ACS Nano, 2023, 17, 13474−13487. 

6. Jiawang Gao, Zhengyuan Guo, Wei Li, Xiaowei Zhang, Xian-En Zhang, Zongqiang Cui*. Ebola virus disrupts the inner blood-retinal barrier by induction of vascular endothelial growth factor in Pericytes. Plos Pathogens, 2023, 19(1) :e1011077.

7. Zhang Xiaowei, Liang Cuiqin, Wang Hanzhong, Guo Zhengyuan, Rong Heng, Pan Jingdi, Li Wei, Pei Rongjuan, Chen Xinwen, Zhang Zhiping, Zhang Xian-En, Cui Zongqiang*. T-Cell Immunoglobulin and Mucin Domain 1 (TIM-1) Is a Functional Entry Factor for Tick-Borne Encephalitis Virus. mBio, 2022, 13(1): e02860-21.

8. Li Wei, Liu Ji, Liu Yuanyuan, Li Qin, Yin Wen, Wanderi Kevin K, Zhang Xiaowei, Zhang Zhiping, Zhang Xian-En, Cui Zongqiang*. HIV-1 uses dynamic podosomes for entry into macrophages. Journal of Virology, 2021, 95(10):e02480-20. 

9. Guo Zhengyuan, Cui Zongqiang*. Fluorescent Nanotechnology for in vivo Imaging. WIREs Nanomed. Nanobiotechnol. 2021, 13 (5): e1705.

10. Zhang Qingrong,Tian Falin,Wang Fei, Guo Zhengyuan, Cai Mingjun, Xu Haijiao, Wang Hongda, Yang Guocheng, Shi Xinghua*, Shan Yuping*, Cui Zongqiang*. Entry Dynamics of Single Ebola Virus Revealed by Force Tracing. ACS Nano, 2020; 14(6): 7046-7054.

11. Chong Qin, Wei Li, Qin Li, Wen Yin, Xiaowei Zhang, Zhiping Zhang, Xian-En Zhang, Zongqiang Cui *. Real-time dissection of dynamic uncoating of individual influenza viruses. PNAS, 2019, 116(7): 2577-2582.