姓 名: 李淑芬 职称职务: 副研究员 电子邮箱:lishufen@wh.iov.cn | |
研究方向 高致病性RNA病毒(布尼亚病毒,新型冠状病毒)感染诱发炎症反应机制及抗炎药物 教育及工作经历 | |
2005.09-2009.06 南昌大学 生命科学学院 生物科学 学士 2009.09-2015.06 中国科学院武汉病毒研究所 微生物学 博士 2015.07-2017.06 广东出入境检验检疫局/广州医科大学 博士后 2017.07-2021.10 中国科学院武汉病毒研究所 助理研究员 2021.10-至今 中国科学院武汉病毒研究所 副研究员 近五年承担项目 | |
1.国家自然科学基金青年项目 2020.01-2022.12 在研 项目负责人 2.中国科学院重点部署项目 2022.01-2023.12 在研 项目负责人 3.国家重点研发计划 2018.05-2023.04 在研 项目骨干
近五年代表性论文 | |
1. Shufen Li#, Hao Li#, YuLan Zhang, Qi-Lin Xin, Zhen-Qiong Guan, Xi Chen Xiao-Ai Zhang, Xiao-Kun Li, Geng-Fu Xiao, Pierre-Yves Lozach, Jun Cui, Wei Liu * Lei-Ke Zhang* and Peng K*. SFTSV Infection Induces BAK/BAX-Dependent Mitochondrial DNA Release to Trigger NLRP3 Inflammasome Activation. Cell Reports. 2020, 30(13):4370-4385. 2. Shufen Li#, Yulan Zhang#, Zhenqiong Guan#, Huiling Li, Meidi Ye, Xi Chen, Jun Shen, Yiwu Zhou, Zhengli Shi, Peng Zhou* and Peng K*. SARS-CoV-2 triggers inflammatory responses and cell death through caspase-8 activation. Signal Transduction and Targeted Therapy. 2020, 5(1):235. 3. Shufen Li*#, Meidi Ye#, Yuanqiao Chen, Yulan Zhang, Jiachen Li, Wei Liu, Hao Li* and Ke Peng*. Screening of a Small Molecule Compound Library Identifies Toosendanin as an Inhibitor Against Bunyavirus and SARS-CoV-2. Frontiers in Pharmacology. 2021, 11:735223. 4. Shufen Li, Xiangtao Zhu, Zhenqiong Guan, Wenfeng Huang, Yulan Zhang, Jeroen Kortekaas, Pierre-Yves Lozach and Ke Peng*. NSs Filament Formation Is Important but Not Sufficient for RVFV Virulence In Vivo. Viruses. 2019, 11(9):834. 5. Shufen Li, Yun Wang, Dianhai Hou, Zhenqiong Guan, Shu Shen, Ke Peng, Fei Deng, Xinwen Chen, Zhihong Hu, Hualin Wang and Manli Wang*. Host factor heat-shock protein 90 contributes to baculovirus budded virus morphogenesis via facilitating nuclear actin polymerization. Virology. 2019, 535: 200-209. 6. Yuanling Yu#, Meiyu Wang#, Xiaoai Zhang#, Shufen Li#, Qingbin Lu, Haolong Zeng, Hongyan Hou, Hao Li, Mengyi Zhang, Fei Jiang, Jiajing Wu, Ruxia Ding, Zehua Zhou, Min Liu, Weixue Si, Tao Zhu, Hangwen Li, Jie Ma, Yuanyuan Gu, Guangbiao She, Xiaokun Li, Yulan Zhang, Ke Peng, Weijin Huang*, Wei Liu* and Youchun Wang*. Antibody-dependent cellular cytotoxicity response to SARS-CoV-2 in COVID-19 patients. Signal Transduction and Targeted Therapy. 2021, 6:346.
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