夏菡

研究方向

兼任中国科学院中非中心分中心副主任、国家病原微生物实验室生物安全评审专家委员、国际病毒分类委员会（ICTV）专家等；《Scientific Data》、《PLoS Neglected Tropical Diseases》和《中国热带医学》等期刊编委。

主要研究方向：

（1）虫媒病毒组、病毒分类鉴定；

（2）虫媒病毒致病性、感染传播风险评估；

（3）大数据和AI驱动的预警预测研究；

（4）国内外生物安全政策规范体系研究。

教育及工作经历

2025.10-现在，中国科学院武汉病毒研究所，研究员

2021.10-2025.10, 中国科学院武汉病毒研究所, 青年研究员

2016.04-2021.10，中国科学院武汉病毒研究所, 副研究员

2013.10-2016.03，美国德克萨斯大学医学部（University of Texas Medical Branch）, 博士后

2011.07-2013.09，中国科学院武汉病毒研究所, 助理研究员

近五年承担项目

(1) 蚊虫防控综合技术研发与示范, 课题负责人, 地方任务, 2024.02—2026.01；

(2) 潜在虫媒新病毒的传播和致病机制研究, 子课题负责人, 国家任务, 2023.12—2026.11；

(3) 虫媒病毒病原发现与感染传播风险研究, 课题负责人, 研究所自主部署, 2023.08—2024.07；

(4) 跨境虫媒传染病新型病原体的发现及感染传播风险研究, 课题负责人, 国家任务, 2022.11—2025.11。

近五年代表性论文

(1) Zhaoyan   Ming, Ying Huang, Cheng Hu, Jiahao Peng, Weijun Sun, Weijin Guo, Tang Sheng,   Huangpu Yuxiang, Zhaolin Li, Xinrui Li, Chen Guanlin, Jicheng Huang, Zhiming   Yuan, Su Kui*, Yongxia Shi*, Han Xia*. AI-Driven Knowledge-Data Graph   for Tracking Global Arbovirus Research. Journal of Big Data,   2025, 12:218.

(2) Xiaoyu   Wang, Ying Huang, Fei Wang, Qianyun Hu, Doudou Huang, Haixia Ma, Yi Liu,   Qiyong Liu, Bo Zhang, Zhiming Yuan*, Han Xia*. DENV-2 3′UTR dumbbell structure is a critical factor for viral infection   and dissemination in Aedes mosquito. Journal of Virology, 2025:   e0075825.

(3) Qun Wu, Dingwei Sun, Wahid Zaman, Fei Wang, Doudou   Huang, Haixia Ma, Shunlong Wang, Ying Liu, Puyu Liu, Xuexia Zeng, Zhiming   Yuan*, Han Xia*. Detection and evolutionary characterization of   arboviruses in mosquitoes and biting midges on Hainan Island, China, 2019–2023. PLoS Neglected   Tropical Diseases, 2024, 18(10): e0012642.

(4)《生物安全导论》中国科学院大学研究生教材/科学出版社十四五高等教育研究生规划教材，主编：袁志明，夏菡，2024，科学出版社.

(5) Shunlong Wang, Ying Huang, Fei Wang, Qian Han,   Nanjie Ren, Xiaoyu Wang, Yingjun Cui*, Zhiming Yuan*, Han Xia*. A cell   atlas of the adult female Aedes aegypti midgut revealed by single-cell RNA   sequencing. Scientific Data, 2024, 11:587.

(6) Zhiqiang Li#, Han Xia#, Guibo Rao#, Yan   Fu, Tingting Chong, Kexing Tian, Zhiming Yuan*, Sheng Cao*. Cryo-EM   structures of Banna virus in multiple states reveal stepwise detachment of   viral spikes. Nature Communications, 2024, 15:2284.

(7) Ying Huang, Shunlong Wang, Hong Liu#, Evans   Atoni, Fei Wang, Wei Chen, Zhaolin Li, Sergio Rodriguez, Zhiming Yuan,   Zhaoyan Ming*, Han Xia*. A global dataset of sequence, diversity and   biosafety recommendation of arbovirus and arthropod-specific virus. Scientific   Data, 2023, 10:305.

(8) Nanjie Ren, Fei Wang, Lu Zhao, Shunlong Wang,   Guilin Zhang, Jiaqi Li, Bo Zhang, Jinglin Wang, Eric Bergeron, Zhiming Yuan*,   Han Xia*. Efficient rescue of a newly classified Ebinur lake   orthobunyavirus with GFP reporter and its application in rapid antiviral   screening. Antiviral Research, 2022, 207: 105421.

(9) Cihan Yang, Fei Wang, Doudou Huang, Haixia Ma,   Lu Zhao, Guilin Zhang, Hailong Li, Qian Han, Dennis Bente, Ferdinand   Villanueva Salazar, Zhiming Yuan*, Han Xia*. Vector competence and   immune response of Aedes aegypti for Ebinur Lake virus, a newly classified   mosquito-borne orthobunyavirus. PLOS Neglected Tropical Diseases,   2022, 16(7): e0010642.

(10) Evans Atoni, Lu Zhao, Cheng Hu, Nanjie Ren,   Xiaoyu Wang, Mengying Liang, Caroline Mwaliko, Zhiming Yuan*and Han Xia*.   A dataset of distribution and diversity of mosquito-associated viruses and   their mosquito vectors in China. Scientific Data, 2020,7:342.